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Meet Our Staff
 
Rahul S. Khupse, Ph.D.
 Assistant Professor, Pharmaceutical Science
 Year Started at UF: 2010
Contact Information
  Office Location: 300 Davis Street #145 A
 Telephone: 419-434-5591
 E-mail: khupse@findlay.edu
Credentials
 

    Profile

    Awards and Honors

    • American Chemical Society, travel grant award for national medicinal chemistry symposium, Seattle: 2006.
    • University of Toledo, Department of Medicinal Chemistry, travel grant award: 2005.
    • Tata Institute of Fundamental Research, India award for foreign studies; 2001.
    • University of Nagpur, Department of Pharmaceutical Sciences, India, Special Distinctions for 1st rank in a class of B. Pharmacy I and III, 2nd rank in a class of B. Pharmacy II and 3rd rank in a class of B. Pharmacy IV: 1997-2001.

    Professional Activity

    Professional Certifications

    • (NABP) National Association of Board of Pharmacy-US Foreign Pharmacy Graduates Equivalency Certification, Dec. 2006.
    • (RAPS) Regulatory Affairs Professionals Society RAC-US Certification, July 2008. 

    Professional Memberships

    • American Association of Cancer Research
    • Sigma Xi, The Scientific Research Society
    • American Chemical Society
    • American Association of Pharmaceutical Scientists

    Recent Publications and/or Performances

    Publications

    Khupse, R.S.; Erhardt, P.W. Total synthesis of xanthohumol Journal of Natural Products 2007, 70(9), 1507-1509.

    Khupse, R. S.; Erhardt, P.W. Practical synthesis of lespedezol A1 Journal of Natural Products 2008, 71(2), 275-277.

    Khupse, R. S.; Erhardt, P. W. Total synthesis of racemic, natural (-) and unnatural(+)-glyceollins I Organic Letters, 2008, 10 (21), 5007–5010.

    Luniwal A.; Khupse R. S, Reese M.; Fang L.; Erhardt P. W; Total Syntheses of  racemic and natural glycinol; Journal of  Natural  Products  2009, 72(11), 2072-2075

    Payton–Stewart, F.; Khupse, R.S.; Boue, S. M.;  Elliot, S.; Zimmermann, C. M.; Skripnikova, E. V.; Ashe, H.; Tighman, S. L.; Beckman, B. S.; McLachlan, J.A.;  Bhatnagar, D.; Wiese, T. E.; Erhardt, P.W.; Burow, M.E.; Glyceollin I enantiomers distinctly regulate ER-mediated gene expression, Steroids, 2010, 75 (12), 870-878.

    Khupse, R.S.; Sarver, J.G.; Trendel, J. A.; Bearss, N. R.; Reese, M. D.; Wiese, T. E.; Boue, S. M.; Burow, M. E.; Cleveland, T. E.; Bhatnagar, D.; Erhardt, P. W.

    Biomimetic syntheses and antiproliferative activities of racemic, natural (-), and unnnatural (+) glyceollin I, Journal of Medicinal Chemistry, 2011 (in press).

    Book Chapter

    Erhardt, P. W.; Khupse, R.S.; Sarver, J. G.; Trendel, J. A. Prodrugs: Strategic Deployment, Metabolic Considerations and Chemical Design Principles, Burger's Medicinal Chemistry, Drug Discovery and Development, 2010.

    Patents

    Methods for synthesizing glyceollins I and II, compositions of selected intermediates, and use in therapeutic applications. (Patent # WO2009/111428).

    Methods for synthesis of xanthohumol. (Patent # WO2009/026206A1).

    Presentations

    •  234th American Chemical Society National Meeting, Boston, (Aug. 2007)
    • 30th National Medicinal Chemistry Symposium, Seattle, (June 2006)
    • 38th Mid Atlantic Graduate Student Symposium, Pittsburgh, (June 2005)
    • Sigma Xi Student Research Symposium, Toledo, (April 2005)
    • 6th Environmental Signaling Network Symposium, New Orleans, (Oct. 2004)